The cannabis plant is highly notable in the research industry due to the 113 beneficial compounds found within the plant. These compounds are known as cannabinoids, and according to research, some of them have been effectively used for providing countless health and industrial benefits for many centuries.
Among the prolonged list of cannabinoids compounds, the one that stands out the most is cannabidiol (CBD). CBD is reaching a new height of fame due to its amazing medical and therapeutic benefits for humans, animals, and industrial uses. It is also expected that the CBD market will generate $2.1 million by the end of 2020.
People worldwide are consuming CBD products, especially CBD oil, but very few know how it works around the body.
So, What Is CBD?
As you know, CBD is a cannabinoid extracted from the Sativa strain in the hemp plant; it is the next cannabinoid after THC (found in abundance in the cannabis plant). However, unlike THC, CBD is non-intoxicating while providing the same proven physical and mental health benefits.
The CBD oil produced from this cannabinoid compound has shown impressive improvement for many health and skin issues.
How CBD Works?
CBD and endocannabinoid system in the human body is correlated to each other. Discovered in the 1980s, endocannabinoid is an intricate system of cell receptors, enzymes, and endocannabinoids with the basic purpose of maintaining the internal equilibrium of the body.
This system controls a wide range of body functions, including sleep, mood swings, pain, immune responses, and appetite, with the assistance of two receptors CB1 and CB2 that control the central and peripheral nervous system, respectively.
Now, CBD works with the endocannabinoid system.
So how is CBD related to the endocannabinoid system within the body? And how does CBD inflicts a positive impact on your medical condition?
According to research, CBD does not directly attach itself to the CB1 and CB2 receptors. But instead, it somehow stimulates the endocannabinoid to release its own cannabinoid.
The enzymes break down the cannabinoids, and the endocannabinoid then binds themselves to the CB1 and CB2 receptors to improve your health. CBD specifically activates these receptors, which exerts a direct positive impact on your health.
How CBD Binds With Receptors?
Research on CBD has concluded that over 60 molecular pathways or ion channels in the human body are affected by this cannabidiol. The data collected below explains how CBD binds with various receptors for creating a therapeutic effect on the body.
- CBD at high concentration directly triggers the 5 -HT1A serotonin receptors, mainly responsible for controlling anxiety, appetite, sleep, pain, nausea, vomiting, and other neurological functions.
- Scientist believes CBD stimulates the TRPV1 receptors, which are generally affiliated with inflammation and pain perceptions and maintain body temperature.
- According to research by the University of Aberdeen in 2010, CBD also blocks certain receptors such as the GPR55, which causes bone reabsorption and weakens cancer cells.
- A healthy intake of CBD can work against the PPAR-gamma receptors, which can help cure Alzheimer’s, diabetes, insulin sensitivity, and other metabolic functions.